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Western blot(SDS PAGE) analysis of extracts from TT cells.Using PC2 Rabbit mAb [AB10] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :PCSK2,NEC2,NEC2_HUMAN,Neuroendocrine convertase 2
UniProtID :P16519
MASS(da) :70,565
MW(kDa) :65-75 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of Human PC2
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :TT cells
Function : Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells..
Subcellular locationi :Cytoplasmic vesicle, secretory vesicle. Secreted.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.