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Western blot(SDS PAGE) analysis of extracts from HeLa cell lysate.Using USP39 Rabbit mAb [o5Fz]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :Inactive ubiquitin specific peptidase 39; SAD1; snRNP ASSEMBLY DEFECTIVE 1; SNRNP65; Ubiquitin specific peptidase 39; USP39;
UniProtID :Q53GS9
MASS(da) :65,381
MW(kDa) :65kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human USP39
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cell lysate.
Function : Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome (PubMed:11350945, PubMed:26912367). Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity (PubMed:18728397)..
Subcellular locationi :Nucleus.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.