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Western blot(SDS PAGE) analysis of extracts from SW480 cell lysate.Using ALDH7A1 Rabbit mAb [PY7S]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :ALDH7A1; Antiquitin; ATQ1; Betaine aldehyde dehydrogenase; EPD; PDE;
UniProtID :P49419
MASS(da) :58,487
MW(kDa) :55kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human ALDH7A1
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :SW480 cell lysate.
Function : Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism..
Tissue specificity :Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue..
Subcellular locationi :[Isoform 2]: Cytoplasm, cytosol. Nucleus.,[Isoform 1]: Mitochondrion.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.