CLIP170 Rabbit mAb [6V2l]Cat NO.: A35728

Protein names ：CLIP; CYLN1; Restin; RSN;

UniProtID ：P30622

MASS(da) ：162,246

MW(kDa) ：130,170kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human CLIP170

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HeLa cell lysate.

Function ： Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking..

Tissue specificity ：Detected in dendritic cells (at protein level). Highly expressed in the Reed-Sternberg cells of Hodgkin disease..

Subcellular locationi ：Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane,Peripheral membrane protein,Cytoplasmic side. Cell projection, ruffle.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.