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Western blot(SDS PAGE) analysis of extracts from various lysates.Using P-CRMP2 (T514) Rabbit mAb [vEl5]at dilution of 1:1000 incubated at 4℃ over night.
Protein names :CRAM; CRMP2; DHPRP2; Dihydropyrimidinase 2; DPYL2; Dpysl2; DRP2; Musunc33; N2A3; TOAD64; Ulip2;
UniProtID :Q16555
MASS(da) :62,294
MW(kDa) :62kDa
Form :Liquid
Purification :Affinity-chromatography
Host :Rabbit
Isotype : IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with A synthesized peptide derived from human Phospho-CRMP2 (T514)
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :various lysates
Function : Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis..
Tissue specificity :Ubiquitous.
Subcellular locationi :Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.