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Integrin alpha 2 Rabbit mAb [VITJ]Cat NO.: A32822

Western blot(SDS PAGE) analysis of extracts from T47-D cells.Using Integrin alpha 2Rabbit mAb [VITJ] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :ITGA2,CD49B,ITA2_HUMAN,Integrin alpha-2

UniProtID :P17301

MASS(da) :129,296

MW(kDa) :150 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human,Mouse

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫组化(IHC)1:100
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Integrin alpha 2

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :T47-D cells

Function : Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix., (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A.., (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8..

Subcellular locationi :Membrane,Single-pass type I membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.