* 产品详情- */>
Western blot(SDS PAGE) analysis of extracts from SH-SY5Y cells.Using ELMO1 Rabbit mAb [EK45] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :ELMO1,KIAA0281,ELMO1_HUMAN,Engulfment and cell motility protein 1
UniProtID :Q92556
MASS(da) :83,829
MW(kDa) :80 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of Human ELMO1
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :SH-SY5Y cells
Function : Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1..
Tissue specificity :Widely expressed, with a higher expression in the spleen and placenta.
Subcellular locationi :Cytoplasm. Cell membrane.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.