SERCA1/ATP2A1 Rabbit mAb[A496]Cat NO.: A67158

Protein names ：ATP2A1,AT2A1_HUMAN,Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 -ATPase 1) ATPase)

UniProtID ：O14983

MASS(da) ：110,252

MW(kDa) ：110kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000,
• 免疫荧光(ICC/IF) 1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human SERCA1/ATP2A1.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Mouse skeletal muscle tissue lysate

Function ： Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity). Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:10914677)..

Tissue specificity ：Skeletal muscle, fast twitch muscle (type II) fibers..

Subcellular locationi ：Endoplasmic reticulum membrane,Multi-pass membrane protein. Sarcoplasmic reticulum membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.