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Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using TMPO/LAP2 Mouse mAb IgG [7HJ8] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :TMPO,LAP2,LAP2B_HUMAN,Lamina-associated polypeptide 2, isoforms beta/gamma [Cleaved into: Thymopoietin ,Thymopentin ]
UniProtID :P42167
MASS(da) :50,670
MW(kDa) :51kDa,39kDa
Form :Liquid
Purification :Protein A purification
Host :Mouse
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human TMPO/LAP2.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HeLa cells
Function : May help direct the assembly of the nuclear lamina and thereby help maintain the structural organization of the nuclear envelope. Possible receptor for attachment of lamin filaments to the inner nuclear membrane. May be involved in the control of initiation of DNA replication through its interaction with NAKAP95., Thymopoietin (TP) and Thymopentin (TP5) may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.
Tissue specificity :Expressed in many tissues. Most abundant in adult thymus and fetal liver.
Subcellular locationi :Nucleus inner membrane,Single-pass type II membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.