FKBP52/FKBP4 Rabbit mAb [2H8K]Cat NO.: A99014

Protein names ：FKBP4,FKBP52,FKBP4_HUMAN,Peptidyl-prolyl cis-trans isomerase FKBP4 [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]

UniProtID ：Q02790

MASS(da) ：51,805

MW(kDa) ：56KDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit monoclonal IgG

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫荧光(ICC/IF) 1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human FKBP52/FKBP4.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：293T cells

Function ： Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria..

Tissue specificity ：Widely expressed..

Subcellular locationi ：Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton. Cell projection, axon.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.