TMPRSS3 Rabbit mAb [N797]Cat NO.: A78078

Protein names ：TMPRSS3,ECHOS1,TADG12,UNQ323/PRO382,TMPS3_HUMAN,Transmembrane protease serine 3

UniProtID ：P57727

MASS(da) ：49,405

MW(kDa) ：49 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100,
• 免疫荧光(ICC/IF)1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human TMPRSS3.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HeLa cells lyastes

Function ： Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro)..

Tissue specificity ：Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.

Subcellular locationi ：Endoplasmic reticulum membrane,Single-pass type II membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.