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Western blot analysis of extracts from Human fetal liver tissue lyaste.using ASGR2 Rabbit mAb [D94S] at dilution of 1:1000 incubated at 4℃ over night
Protein names :ASGR2,CLEC4H2,ASGR2_HUMAN,Asialoglycoprotein receptor 2
UniProtID :P07307
MASS(da) :35,092
MW(kDa) :46 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human ASGR2.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human fetal liver tissue lyaste
Function : Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Tissue specificity :Expressed exclusively in hepatic parenchymal cells.
Subcellular locationi :Membrane,Single-pass type II membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.