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Western blot analysis of extracts from K-562 cells lyastes.using kur Rabbit mAb [1WA0] at dilution of 1:1000 incubated at 4℃ over night
Protein names :CFAP298,C21orf48,C21orf59,CF298_HUMAN,Cilia- and flagella-associated protein 298
UniProtID :P57076
MASS(da) :33,224
MW(kDa) :33 kda
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human kur.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :K-562 cells lyastes
Function : Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity)..
Subcellular locationi :Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.