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Western blot analysis of extracts from Human muscle tissue lyaste.using Claudin 17 Rabbit mAb [N81A] at dilution of 1:1000 incubated at 4℃ over night
Protein names :CLDN17,UNQ758/PRO1489,CLD17_HUMAN,Claudin-17
UniProtID :P56750
MASS(da) :24,603
MW(kDa) :25 kda
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human Claudin 17.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human muscle tissue lyaste
Function : Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability..
Tissue specificity :In the kidney, expressed in the proximal tubule and in the Henle's loop. In the distal convoluted tubule, not expressed in all tubules. Not detected in the collecting duct (at protein level)..
Subcellular locationi :Cell junction, tight junction. Cell membrane,Multi-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.