P-Mcl-1 (T163) Rabbit mAb [5SAL]Cat NO.: A40668

Protein names ：MCL1,BCL2L3,MCL1_HUMAN,Induced myeloid leukemia cell differentiation protein Mcl-1

UniProtID ：Q07820

MASS(da) ：37,337

MW(kDa) ：40 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of Human Phospho-Mcl-1 (Thr163)

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：KARPAS-299 cells treated with TPA (200 nM 30 min )

Function ： Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis..

Subcellular locationi ：Membrane,Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.