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Western blot(SDS PAGE) analysis of extracts from Jurkat cells.Using GNAQ Mouse mAb [P3RT] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :GNAQ,GAQ,GNAQ_HUMAN,Guanine nucleotide-binding protein G subunit alpha
UniProtID :P50148
MASS(da) :42,142
MW(kDa) :42 kd
Form :Liquid
Purification :Protein A purification
Host :Mouse
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Rat,Mouse
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human GNAQ
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Jurkat cells
Function : Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs)..
Tissue specificity :Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level)..
Subcellular locationi :Cell membrane,Lipid-anchor. Golgi apparatus. Nucleus. Nucleus membrane.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.